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Ji-Long Chen Selected Research

eIF-4B

1/2021Deficiency of eIF4B Increases Mouse Mortality and Impairs Antiviral Immunity.
3/2016eIF4B is a convergent target and critical effector of oncogenic Pim and PI3K/Akt/mTOR signaling pathways in Abl transformants.
8/2014Influenza A virus-induced degradation of eukaryotic translation initiation factor 4B contributes to viral replication by suppressing IFITM3 protein expression.
8/2013eIF4B phosphorylation by pim kinases plays a critical role in cellular transformation by Abl oncogenes.

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Ji-Long Chen Research Topics

Disease

30Infections
09/2022 - 05/2012
24Virus Diseases (Viral Diseases)
11/2022 - 05/2012
9Neoplasms (Cancer)
01/2022 - 08/2013
7Carcinogenesis
01/2022 - 06/2012
5Leukemia
01/2019 - 01/2014
2Bites and Stings (Sting)
11/2022 - 08/2017
2Human Influenza (Influenza)
02/2021 - 10/2018
2Inflammation (Inflammations)
01/2021 - 01/2021
1Starvation
12/2021
1Coinfection
01/2021
1Pneumonia (Pneumonitis)
01/2021
1Precursor Cell Lymphoblastic Leukemia-Lymphoma (Acute Lymphoblastic Leukemia)
01/2019
1Lymphoma (Lymphomas)
08/2017
1Viral Zoonoses
04/2016
1Reoviridae Infections
02/2015
1Weight Loss (Weight Reduction)
08/2014
1BCR-ABL Positive Chronic Myelogenous Leukemia (Chronic Myelogenous Leukemia)
06/2012
1Vesicular Stomatitis
09/2002

Drug/Important Bio-Agent (IBA)

17InterferonsIBA
11/2022 - 01/2014
17Antiviral Agents (Antivirals)IBA
11/2022 - 01/2014
9CytokinesIBA
01/2021 - 01/2014
8Proteins (Proteins, Gene)FDA Link
11/2022 - 08/2014
8Long Noncoding RNAIBA
01/2022 - 05/2014
5Imatinib Mesylate (Gleevec)FDA Link
01/2022 - 08/2013
5Interferon LambdaIBA
01/2017 - 01/2014
4Interleukin-6 (Interleukin 6)IBA
09/2022 - 02/2016
4eIF-4BIBA
01/2021 - 08/2013
3Messenger RNA (mRNA)IBA
09/2022 - 02/2016
3Phosphotransferases (Kinase)IBA
01/2022 - 11/2018
3RNA (Ribonucleic Acid)IBA
01/2022 - 01/2019
2Glycoproteins (Glycoprotein)IBA
09/2022 - 12/2014
2Protein Kinases (Protein Kinase)IBA
12/2021 - 12/2015
2Untranslated RNA (Noncoding RNA)IBA
01/2021 - 05/2014
2MicroRNAs (MicroRNA)IBA
01/2021 - 01/2019
2Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA
01/2020 - 02/2016
2Oncogene Proteins (Oncogene Protein)IBA
12/2018 - 08/2017
2Tyrosine (L-Tyrosine)FDA Link
11/2018 - 06/2012
2Biomarkers (Surrogate Marker)IBA
05/2016 - 01/2016
1cyclic guanosine monophosphate-adenosine monophosphateIBA
11/2022
1Poly I-CIBA
11/2022
1NeuropeptidesIBA
09/2022
1Double-Stranded RNA (RNA, Double Stranded)IBA
12/2021
1IronIBA
12/2021
1Competitive Endogenous RNAIBA
10/2021
1Plant ExtractsIBA
02/2021
1Pharmaceutical PreparationsIBA
02/2021
1Extracellular Signal-Regulated MAP Kinases (Extracellular Signal Regulated Kinases)IBA
01/2021
1Epidermal Growth Factor (EGF)IBA
01/2021
1Piwi-Interacting RNAIBA
01/2021
1Circular RNAIBA
01/2021
1Amyloid (Amyloid Fibrils)IBA
01/2021
1DNA (Deoxyribonucleic Acid)IBA
01/2021
1Nitric Oxide Synthase (NO Synthase)IBA
01/2021
1ChemokinesIBA
01/2021
1Protein Tyrosine PhosphatasesIBA
01/2021
1Biological ProductsIBA
01/2021
1neuromedin BIBA
10/2019
1NF-kappa B (NF-kB)IBA
01/2019
1Non-Receptor Type 1 Protein Tyrosine PhosphataseIBA
01/2019
1Mitogen-Activated Protein Kinase Kinases (MEKs)IBA
12/2018
1bcr-abl Fusion ProteinsIBA
12/2018
1Collectins (Collectin)IBA
01/2018
1Interferon-betaIBA
05/2017
1butyl phosphorotrithioate (DEF)IBA
01/2017
1Hemagglutinins (Hemagglutinin)IBA
04/2016
1Small Interfering RNA (siRNA)IBA
04/2016
1Interferon Type IIBA
02/2016
1Toll-Like Receptors (Toll-Like Receptor)IBA
02/2016
1InterleukinsIBA
02/2016
1Neuraminidase (Sialidase)IBA
12/2014
1Phosphoric Monoester Hydrolases (Phosphatases)IBA
01/2014
1proto-oncogene proteins pimIBA
08/2013
1Suppressor of Cytokine Signaling ProteinsIBA
06/2012
1Phospholipases (Phospholipase)IBA
05/2012
1Protein-Tyrosine Kinases (Tyrosine Kinase)IBA
05/2012
1AcidsIBA
09/2002
11,2-bis(2-aminophenoxy)ethane N,N,N',N'-tetraacetic acid acetoxymethyl esterIBA
09/2002
1Shiga Toxin (Shigella Toxin)IBA
09/2002
1Calcium Chelating AgentsIBA
09/2002
1EstersIBA
09/2002

Therapy/Procedure

4Therapeutics
12/2018 - 01/2014